Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18479638 | 0.89 | RORC (0.81) | RORC | |
| SCHEMBL18479639 | 0.89 | RORC (0.81) | RORC | |
| SCHEMBL21750503 | 0.89 | RORC (0.81) | RORC | |
| SCHEMBL22512543 | 0.88 | RORC (0.64) | RORC | |
| SCHEMBL22512498 | 0.85 | RORC (0.59) | RORC | |
| SCHEMBL21750500 | 0.78 | RORC (1.00) | RORC | |
| SCHEMBL22490687 | 0.78 | RORC (1.00) | RORC | |
| SCHEMBL21750526 | 0.78 | RORC (1.00) | RORC | |
| SCHEMBL20454463 | 0.78 | RORC (0.77) | RORC | |
| SCHEMBL21750578 | 0.77 | RORC (0.88) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024018-A1 | MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, INC. (US) | 2017-02-09 | — | — | WO | disclosed |