Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20714587 | 0.93 | METAP1 (0.31) | METAP1 | |
| SCHEMBL24722286 | 0.82 | METAP1 (0.33) | METAP1 | |
| SCHEMBL19063319 | 0.82 | METAP1 (0.33) | METAP1 | |
| SCHEMBL22064767 | 0.80 | — | — | |
| SCHEMBL20609967 | 0.73 | TSHR (0.40) | METAP1 | |
| SCHEMBL24925671 | 0.72 | — | — | |
| SCHEMBL20609978 | 0.71 | METAP1 (0.36) | METAP1 | |
| SCHEMBL21440306 | 0.70 | DNM1 (0.36) | — | |
| SCHEMBL22641435 | 0.70 | METAP1 (0.32) | METAP1 | |
| SCHEMBL20928522 | 0.70 | METAP1 (0.32) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023989-A1 | 3-(1H-BENZO[D]IMIDAZOL-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | disclosed |