Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18482335 | 0.95 | SLC34A2 (0.48) | SLC34A2BRAFKDM4ERAF1ROCK2 | |
| SCHEMBL18482337 | 0.91 | SLC34A2 (0.57) | SLC34A2BRAFKDM4ERAF1ROCK2 | |
| SCHEMBL18484278 | 0.91 | SLC34A2 (0.46) | SLC34A2BRAFRAF1KCNH2 | |
| SCHEMBL18482333 | 0.89 | SLC34A2 (0.47) | SLC34A2BRAFKDM4ERAF1ROCK2 | |
| SCHEMBL18482336 | 0.89 | SLC34A2 (0.50) | SLC34A2BRAFKDM4ERAF1ROCK2 | |
| SCHEMBL18482722 | 0.86 | SLC34A2 (0.50) | SLC34A2BRAFKDM4ERAF1ROCK2 | |
| SCHEMBL18482329 | 0.86 | SLC34A2 (0.47) | SLC34A2BRAFKDM4ERAF1TEK | |
| SCHEMBL6002461 | 0.86 | SLC34A2 (0.52) | SLC34A2BRAFKDM4ERAF1ROCK2 | |
| SCHEMBL18482256 | 0.85 | SLC34A2 (0.46) | SLC34A2BRAFKDM4ERAF1KCNH2 | |
| SCHEMBL18482986 | 0.85 | SLC34A2 (0.45) | SLC34A2BRAFKDM4ERAF1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037010-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037010-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A2, SLC34A1, SLC10A2 | SLC34A2 1/4885BRAF 3436/4885KDM4E 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.