Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 15/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.51 |
| ▸ | CLK3 | P49761 | 13/20 | 0.51 |
| ▸ | WNT1 | P04628 | 5/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18452083 | 0.93 | CLK2 (0.52) | CLK2DYRK1ACLK3WNT1TGFBR1 | |
| SCHEMBL18485805 | 0.90 | CLK2 (0.54) | CLK2DYRK1ACLK3WNT1TGFBR1 | |
| SCHEMBL18483116 | 0.90 | CLK3 (0.55) | CLK2DYRK1ACLK3WNT1 | |
| SCHEMBL18453064 | 0.90 | CLK2 (0.55) | CLK2DYRK1ACLK3WNT1TGFBR1 | |
| SCHEMBL18447629 | 0.87 | CLK2 (0.65) | CLK2DYRK1ACLK3WNT1 | |
| SCHEMBL18452445 | 0.87 | DYRK1A (0.54) | CLK2DYRK1ACLK3WNT1TGFBR1 | |
| SCHEMBL18483264 | 0.87 | CLK2 (0.54) | CLK2DYRK1ACLK3WNT1 | |
| SCHEMBL20452893 | 0.87 | CLK2 (0.53) | CLK2DYRK1ACLK3WNT1TGFBR1 | |
| SCHEMBL20467182 | 0.87 | WNT1 (0.48) | CLK2DYRK1ACLK3WNT1 | |
| SCHEMBL18485826 | 0.86 | CLK2 (0.49) | CLK2DYRK1ACLK3WNT1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023981-A1 | 3-(1H-PYRROLO[2,3-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | disclosed |