Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.34 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18471598 | 0.87 | HDAC1 (0.42) | HDAC1HDAC6SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2926843 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AMEN1CYP2C19NPSR1 | |
| SCHEMBL2921169 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1CYP2C19NPSR1 | |
| SCHEMBL2921535 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1CYP2C19NPSR1 | |
| SCHEMBL2929524 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AMEN1CYP2C19NPSR1 | |
| SCHEMBL2923195 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1CYP2C19NPSR1 | |
| SCHEMBL2927272 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1CYP2C19NPSR1 | |
| SCHEMBL2928406 | 0.81 | SMN1; SMN2 (0.43) | HDAC1SMN1; SMN2KMT2AMEN1CYP2C19 | |
| SCHEMBL18484169 | 0.81 | AURKA (0.47) | SMN1; SMN2KMT2AMEN1HTTMAPT | |
| SCHEMBL4778421 | 0.79 | ATM (0.38) | NPSR1ATMMAPTLMNAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969753-B2 | BCR-ABL diploid inhibitor, synthesizing method therefor, and uses thereof | SHENZHEN YONGZE PHARMACEUTICAL CO., LTD. (CN) | 2018-05-15 | — | — | US | disclosed |
| US-20170037061-A1 | BCR-ABL Diploid Inhibitor, Synthesizing Method Therefor, and Uses Thereof | SHENZHEN YONGZE PHARMACEUTICAL CO., LTD. (CN) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037061-A1 | BCR-ABL Diploid Inhibitor, Synthesizing Method Therefor, and Uses Thereof | BCR, ABL1, BOD1L1 | HDAC1 1785/4885HDAC6 1983/4885SMN1; SMN2 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.