SCHEMBL1848490

SCHEMBL1848490

C/C=C/C(O)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12122486 1.00
SCHEMBL1848491 1.00
SCHEMBL12124671 1.00
SCHEMBL5380377 1.00
SCHEMBL10613631 1.00
Ethylene Glycol SCHEMBL1425224 0.94 AKR1B1 (0.39)
Ethylene Glycol SCHEMBL6673939 0.94 AKR1B1 (0.39)
SCHEMBL8014451 0.79 AKR1B1 (0.53)
SCHEMBL8014456 0.79 AKR1B1 (0.53)
SCHEMBL7122448 0.78 AKR1B1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110282075-A1 METHOD FOR PREPARING VITTATALACTONE ALBERT-LUDWIGS-UNIVERSITAT FREIBURG (DE) 2011-11-17 US disclosed
US-20110190511-A1 Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto IM&T RESEARCH, INC. (US) 2011-08-04 US disclosed
EP-2323974-A1 METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO Ube Industries, Ltd. (JP) 2011-05-25 EP disclosed
US-20100152463-A1 Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto IM&T RESEARCH, INC. (US) 2010-06-17 US disclosed
WO-2010022001-A1 METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO IM&T RESEARCH, INC. (US) 2010-02-25 WO disclosed
US-7199252-B2 Process for α,β-dihydroxyalkenes and derivatives EASTMAN CHEMICAL COMPANY (US) 2007-04-03 US disclosed
US-20070004664-A1 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) SIRNA THERAPEUTICS, INC. (US) 2007-01-04 US disclosed
US-20060189774-A1 Modifiable polyunsaturated polymers and processes for their preparation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2006-08-24 US disclosed
US-7002049-B2 Process for α,β-dihydroxyalkenes and derivatives EASTMAN CHEMICAL COMPANY (US) 2006-02-21 US disclosed
US-20060030742-A1 Process for alpha,beta-dihydroxyalkenes and derivatives HEMBRE ROBERT T 2006-02-09 US disclosed
US-6313343-B1 OXIDATION CATALYSTS NIPPON SHOKUBAI CO., LTD. (JP) 2001-11-06 US disclosed
EP-0760358-B1 Method of manufacturing alpha-oxocarboxylate and catalyst adopted in the method NIPPON CATALYTIC CHEM IND (JP) 2001-06-20 EP disclosed
EP-1000920-A1 PROCESS FOR THE PREPARATION OF $g(a)-OXOALDEHYDES Nippon Shokubai Co., Ltd. (JP) 2000-05-17 EP disclosed
US-5750768-A Method of manufacturing α-oxocarboxylate and catalyst adopted in the method NIPPON SHOKUBAI CO., LTD. (JP) 1998-05-12 US disclosed
EP-0760358-A1 Method of manufacturing alpha-oxocarboxylate and catalyst adopted in the method NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-05 EP disclosed
US-4661646-A Process for the preparation of 1-butene-3,4-diol BAYER AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
EP-0142657-B1 PROCESS FOR THE PRODUCTION OF 1-BUTENE-3,4-DIOL BAYER AG (DE) 1986-12-30 EP disclosed
EP-0142657-A1 Process for the production of 1-butene-3,4-diol BAYER AG (DE) 1985-05-29 EP disclosed
US-4292151-A MELT SPINNING THE BLOCK POLYMER WITH AN UNSATURATED COMPOUND; CURING WITH ACTINIC RADIATION TEIJIN LIMITED (JP) 1981-09-29 US disclosed
US-4289915-A Halogenated polyhydroxy compounds and their derivatives PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1981-09-15 US disclosed