Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848355 | 0.97 | GPR52 (0.78) | GPR52MAPK1MTNR1AMTNR1BSNCA | |
| SCHEMBL1848932 | 0.92 | GPR52 (0.73) | GPR52SNCA | |
| SCHEMBL1853839 | 0.91 | GPR52 (0.77) | GPR52SNCA | |
| SCHEMBL1851459 | 0.90 | GPR52 (0.80) | GPR52SNCA | |
| SCHEMBL1847900 | 0.89 | GPR52 (0.75) | GPR52NR4A2 | |
| SCHEMBL3206518 | 0.88 | GPR52 (0.78) | GPR52SNCA | |
| SCHEMBL3208303 | 0.87 | GPR52 (0.82) | GPR52SNCA | |
| SCHEMBL3217725 | 0.87 | GPR52 (0.79) | GPR52SNCA | |
| SCHEMBL3217749 | 0.87 | GPR52 (0.75) | GPR52SNCA | |
| SCHEMBL1850246 | 0.86 | GPR52 (0.77) | GPR52SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |