Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290795 | 0.95 | EPHX1 (0.39) | EPHX1ACP3MIFSLC6A2SLC6A4 | |
| SCHEMBL10793721 | 0.88 | MEN1 (0.41) | MIFCYP2C19PKMSMN1; SMN2 | |
| SCHEMBL10796625 | 0.88 | MEN1 (0.41) | MIFCYP2C19PKMSMN1; SMN2 | |
| SCHEMBL5693998 | 0.87 | CYP3A4 (0.44) | EPHX1ACP3MIFSLC6A2SLC6A4 | |
| SCHEMBL16279597 | 0.87 | CYP3A4 (0.49) | EPHX1ACP3MIFSLC6A2SLC6A4 | |
| SCHEMBL4640624 | 0.82 | MIF (0.46) | MIFCYP2D6TSHRCYP2C19TAAR1 | |
| SCHEMBL6386364 | 0.81 | MIF (0.65) | EPHX1ACP3MIFSLC6A2SLC6A4 | |
| SCHEMBL6970517 | 0.78 | MIF (0.67) | MIFCYP2C19 | |
| SCHEMBL4352912 | 0.78 | MIF (0.43) | MIFCYP2D6CYP2C19 | |
| SCHEMBL3585197 | 0.78 | MIF (0.43) | MIFCYP2D6CYP2C19TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026568-A | Slow-release anti-icing polyurethane mixture suitable for steel bridge deck and preparation method thereof | 浙江交投丽新矿业有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-108779096-B | Fluorine-substituted cyclopropylamine compounds, and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-07-01 | — | — | CN | disclosed |
| CN-106458485-B | Paper supply transport roller and its manufacturing method | 新智德株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-107466310-A | Polyamide with improved optical characteristics | 巴斯夫欧洲公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-107075075-A | The purposes of thermoplastic polyurethane powder | 科思创德国股份有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104704017-B | The preparation and use of TPUE based on polyether carbonate polyol | 科思创德国股份有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-106794686-A | The permeable composite component of water vapour | 科思创德国股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106458485-A | Paper feed and conveyance roll and production method therefor | 新智德株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-106459348-A | Thermoplastic polyurethanes, production and use thereof | 科思创德国股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-102015862-B | Halogen-free flame-retardant TPU | BASF SE (DE) | 2016-03-30 | — | — | CN | disclosed |
| CN-102382277-B | Thermoplastically processable polyurethanes based on propylene glycol succinate | BAYER MATERIALSCIENCE AG | 2015-04-01 | — | — | CN | disclosed |
| CN-101341199-B | Reduction of transfer of vibrations | HENKEL AG & CO KGAA | 2012-03-28 | — | — | CN | disclosed |
| EP-2323659-A1 | COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES | Abbott Laboratories (US) | 2011-05-25 | — | — | EP | disclosed |
| CN-101743262-A | thermoplastic polyurethane with antistatic properties | BASF SE | 2010-06-16 | — | — | CN | disclosed |
| WO-2010017150-A1 | COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES | ABBOTT LABORATORIES (US) | 2010-02-11 | — | — | WO | disclosed |
| CN-101341199-A | Reduction of transfer of vibrations | HENKEL AG & CO KGAA (DE) | 2009-01-07 | — | — | CN | disclosed |