SCHEMBL28290795

SCHEMBL28290795

N=C=O.O=C=NC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.39
ACP3 P15309 1/20 0.39
MIF P14174 1/20 0.39
SLC6A2 P23975 3/20 0.37
SLC6A4 P31645 3/20 0.37
SLC6A3 Q01959 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
SIGMAR1 Q99720 1/20 0.35
ALPI P09923 1/20 0.34
PKM P14618 1/20 0.34
PTGS1 P23219 1/20 0.34
XIAP P98170 1/20 0.34
SLC7A5 Q01650 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HTT P42858 1/20 0.34
NCOA1 Q15788 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1848616 0.95 EPHX1 (0.42) EPHX1ACP3MIFSLC6A2SLC6A4
SCHEMBL28119584 0.83 ACP3 (0.41) ACP3MIFSLC6A2SLC6A4SLC6A3
SCHEMBL10796625 0.83 MEN1 (0.41) MIFCYP2C19PKMSMN1; SMN2
SCHEMBL10793721 0.83 MEN1 (0.41) MIFCYP2C19PKMSMN1; SMN2
SCHEMBL16279597 0.82 CYP3A4 (0.49) EPHX1ACP3MIFSLC6A2SLC6A4
SCHEMBL5693998 0.82 CYP3A4 (0.44) EPHX1ACP3MIFSLC6A2SLC6A4
SCHEMBL4640624 0.77 MIF (0.46) MIFCYP2D6TSHRCYP2C19TAAR1
SCHEMBL6386364 0.77 MIF (0.65) EPHX1ACP3MIFSLC6A2SLC6A4
SCHEMBL3585197 0.74 MIF (0.43) MIFCYP2D6CYP2C19TAAR1
SCHEMBL4352912 0.74 MIF (0.43) MIFCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106255717-B Flame retardant thermoplastic polyurethanes 巴斯夫欧洲公司 2019-05-07 CN disclosed