Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 10/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689071 | 1.00 | TYMP (0.39) | TYMPADORA1NNMTEGFRERBB2 | |
| SCHEMBL17363634 | 0.95 | TYMP (0.38) | TYMPADORA1NNMT | |
| SCHEMBL17363637 | 0.95 | TYMP (0.38) | TYMPADORA1NNMT | |
| SCHEMBL24191249 | 0.88 | TYMP (0.47) | TYMPADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL24191301 | 0.88 | ADORA1 (0.43) | TYMPADORA1NNMTEGFRERBB2 | |
| SCHEMBL16871849 | 0.88 | TYMP (0.41) | TYMPADORA1 | |
| SCHEMBL16871825 | 0.88 | TYMP (0.38) | TYMPADORA1NNMT | |
| SCHEMBL18486397 | 0.88 | SLC28A2 (0.34) | TYMP | |
| SCHEMBL19689094 | 0.88 | SLC28A2 (0.34) | TYMP | |
| SCHEMBL16326598 | 0.87 | TYMP (0.40) | TYMPADORA1PRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130597-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | Kyowa Hakko Kirin Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |