Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18486383 | 1.00 | STING1 (0.35) | STING1P2RY12CYP1A2PDE4APDE4B | |
| SCHEMBL17363609 | 0.91 | STING1 (0.34) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16871715 | 0.91 | STING1 (0.34) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18486404 | 0.86 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18486251 | 0.86 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16871895 | 0.83 | DNPH1 (0.44) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17363663 | 0.83 | DNPH1 (0.44) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17363528 | 0.83 | PDE4A (0.44) | STING1CYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL17363529 | 0.83 | PDE4A (0.44) | STING1CYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL19689068 | 0.82 | STING1 (0.38) | STING1CYP1A2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130597-B1 | OLIGONUCLEOTIDE HAVING A NON-NATURAL NUCLEOTIDE AT THE 5'-TERMINAL | KYOWA KIRIN CO LTD (JP) | 2021-11-10 | — | — | EP | disclosed |
| EP-3130597-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | Kyowa Hakko Kirin Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |