Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ribavirin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.82 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.82 |
| ▸ | THPO | P40225 | 2/20 | 0.82 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.82 |
| ▸ | GLA | P06280 | 1/20 | 0.82 |
| ▸ | EIF4E | P06730 | 1/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
| ▸ | TOP1 | P11387 | 1/20 | 0.82 |
| ▸ | PNP | P00491 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATIC | P31939 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribavirin SCHEMBL572829 | 0.93 | LMNA (0.90) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL1200226 | 0.93 | LMNA (0.90) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL5473652 | 0.92 | LMNA (0.88) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL2619251 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL12658449 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL3727 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL6027558 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL20806078 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL21311208 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR | |
| Ribavirin SCHEMBL5476700 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1ADORA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110658279-B | Method for detecting ribavirin and metabolites thereof in livestock and poultry hair | 江西省农业科学院农产品质量安全与标准研究所 | 2022-07-15 | — | — | CN | disclosed |
| CN-110658279-A | Method for detecting ribavirin and metabolites thereof in livestock and poultry hair | 江西省农业科学院农产品质量安全与标准研究所 | 2020-01-07 | — | — | CN | disclosed |
| US-10103401-B2 | Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same | TORAY INDUSTRIES, INC. (JP) | 2018-10-16 | — | — | US | disclosed |
| EP-3131145-B1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME | TORAY INDUSTRIES (JP) | 2018-09-05 | — | — | EP | disclosed |
| US-20170125832-A1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2017-05-04 | — | — | US | disclosed |
| EP-3131145-A1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME | Toray Industries, Inc. (JP) | 2017-02-15 | — | — | EP | disclosed |