Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559838 | 0.88 | POLB (0.44) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL24440813 | 0.87 | MAPT (0.42) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL16559840 | 0.87 | POLB (0.40) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL24440871 | 0.86 | POLB (0.43) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL23643324 | 0.86 | HTT (0.40) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL16559829 | 0.84 | POLB (0.47) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL17538614 | 0.84 | POLB (0.43) | POLBAPEX1HTTTDP1PPARG | |
| SCHEMBL24440804 | 0.83 | POLB (0.41) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL15338931 | 0.83 | POLB (0.51) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL19158978 | 0.83 | FFAR1 (0.40) | POLBAPEX1HTTTDP1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037315-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | US | disclosed |