Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810285 | 0.91 | REN (0.40) | RENCNR1 | |
| SCHEMBL13131643 | 0.85 | REN (0.58) | REN | |
| SCHEMBL2805691 | 0.84 | REN (0.41) | REN | |
| SCHEMBL2849844 | 0.82 | REN (0.40) | REN | |
| SCHEMBL13132613 | 0.82 | REN (0.44) | REN | |
| SCHEMBL13132742 | 0.81 | REN (0.40) | REN | |
| SCHEMBL13132857 | 0.81 | REN (0.40) | REN | |
| SCHEMBL13132201 | 0.80 | REN (0.42) | REN | |
| SCHEMBL13132488 | 0.80 | REN (0.49) | REN | |
| SCHEMBL13132199 | 0.79 | REN (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |