Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062037 | 0.85 | — | — | |
| SCHEMBL11489750 | 0.81 | TSHR (0.56) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL11489752 | 0.81 | TSHR (0.56) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL7349581 | 0.79 | MEN1 (0.42) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL15796470 | 0.79 | TSHR (0.53) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL20149545 | 0.78 | — | — | |
| SCHEMBL272770 | 0.78 | — | — | |
| SCHEMBL6062833 | 0.78 | GAA (0.37) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL8748516 | 0.78 | GAA (0.37) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL15112 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048407-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2020-02-13 | — | — | US | disclosed |
| US-20180215865-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-08-02 | — | — | US | disclosed |
| WO-2017023506-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215865-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | DTYMK, DDOST, DDT | TSHR 4029/4885MAPK1 4540/4885MEN1 1813/4885 |
| US-20200048407-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | DTYMK, DDOST, DDT | TSHR 4029/4885MAPK1 4540/4885MEN1 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.