Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324088 | 0.88 | IDH1 (0.42) | KDM4EALDH1A1GLAIDH1NQO2 | |
| SCHEMBL15866033 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1GLAMTNR1AEPHX1 | |
| SCHEMBL24204874 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1IDH1NQO2MTNR1A | |
| SCHEMBL18470681 | 0.79 | IDH1 (0.43) | IDH1NQO2MTNR1AMTNR1BTHRA | |
| SCHEMBL19558277 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL20099484 | 0.78 | TDP1 (0.49) | KDM4EALDH1A1GLAMTNR1AMTNR1B | |
| SCHEMBL30727531 | 0.76 | IDH1 (0.54) | IDH1MTNR1AMTNR1BTHRATHRB | |
| SCHEMBL3952728 | 0.76 | IDH1 (0.54) | IDH1MTNR1AMTNR1BTHRATHRB | |
| SCHEMBL29418808 | 0.76 | IDH1 (0.54) | IDH1MTNR1AMTNR1BTHRATHRB | |
| SCHEMBL17938431 | 0.76 | NPC1 (0.49) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957339-B2 | Copolymer and associated layered article, and device-forming method | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170037171-A1 | COPOLYMER AND ASSOCIATED LAYERED ARTICLE, AND DEVICE-FORMING METHOD | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-02-09 | — | — | US | disclosed |