Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 3/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 5/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846958 | 0.88 | MEN1 (0.36) | MGAT2EP300MOGAT2CYP2C9 | |
| SCHEMBL1846837 | 0.84 | PRKAB2 (0.37) | MGAT2EP300PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1848884 | 0.81 | OPRL1 (0.38) | MGAT2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| Hydrochloric Acid SCHEMBL2159448 | 0.81 | OPRL1 (0.37) | MGAT2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL476344 | 0.78 | CNR1 (0.31) | — | |
| SCHEMBL1847077 | 0.77 | EP300 (0.36) | MGAT2EP300PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1847309 | 0.77 | EP300 (0.36) | MGAT2EP300PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1848054 | 0.77 | PRKAB2 (0.38) | EP300PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1848735 | 0.75 | PRKAB2 (0.34) | MGAT2EP300PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1846655 | 0.75 | PRKAB2 (0.34) | MGAT2EP300PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324015-A2 | THIOPHENE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-aventis (FR) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010012964-A2 | THIOPHENE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-02-04 | — | — | WO | disclosed |