Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851435 | 0.84 | HSD17B10 (0.48) | KDM4EL3MBTL1ALDH1A1JAK2JAK1 | |
| SCHEMBL1853420 | 0.77 | DAO (0.46) | ALDH1A1CCNCCDK8LMNA | |
| SCHEMBL1850221 | 0.75 | CYP2A6 (0.33) | STING1PKM | |
| SCHEMBL18264010 | 0.75 | HSD17B10 (0.47) | KDM4EL3MBTL1ALDH1A1JAK2JAK1 | |
| SCHEMBL18264017 | 0.73 | HSD17B10 (0.51) | KDM4EL3MBTL1ALDH1A1JAK2JAK1 | |
| SCHEMBL1852613 | 0.73 | HSD17B10 (0.39) | KDM4EL3MBTL1ALDH1A1JAK2JAK1 | |
| SCHEMBL1850208 | 0.72 | — | — | |
| SCHEMBL18264005 | 0.72 | HSD17B10 (0.52) | KDM4EL3MBTL1ALDH1A1JAK2JAK1 | |
| SCHEMBL26622028 | 0.71 | HSD17B10 (0.49) | KDM4EL3MBTL1ALDH1A1JAK2JAK1 | |
| SCHEMBL1855350 | 0.69 | HSD17B10 (0.47) | KDM4EL3MBTL1ALDH1A1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |