Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.32 |
| ▸ | CLK3 | P49761 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312255 | 0.87 | KMT2A (0.46) | KMT2ASCN9ACYP19A1KDM4EPOLB | |
| SCHEMBL17571471 | 0.81 | KMT2A (0.41) | KMT2ASCN9ACYP19A1KDM4EPOLB | |
| SCHEMBL18474532 | 0.81 | KMT2A (0.41) | KMT2ASCN9ACYP19A1KDM4EPOLB | |
| SCHEMBL15301413 | 0.79 | KMT2A (0.40) | KMT2ASCN9ACYP19A1KDM4EPOLB | |
| SCHEMBL14785048 | 0.78 | IDO1 (0.33) | CA2CA1PTGS2 | |
| SCHEMBL18475990 | 0.78 | KMT2A (0.39) | KMT2ASCN9ACYP19A1KDM4EPOLB | |
| SCHEMBL19022210 | 0.77 | GRIA4 (0.39) | KMT2AKDM4EPOLBTSHRRECQL | |
| SCHEMBL17562440 | 0.77 | KMT2A (0.38) | KMT2ASCN9ACYP19A1KDM4EPOLB | |
| SCHEMBL1542377 | 0.74 | CYP19A1 (0.61) | KMT2ACYP19A1KDM4EPOLBTSHR | |
| SCHEMBL15218453 | 0.74 | KMT2A (0.47) | KMT2ACYP19A1KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023986-A1 | 3-(1H-INDOL-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2017-02-09 | — | — | WO | disclosed |