Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849006 | 0.75 | HPGD (0.42) | HPGDEPHX1CTSKSMN1; SMN2USP2 | |
| SCHEMBL5278772 | 0.73 | HPGD (0.40) | HPGDEPHX1CTSKSMN1; SMN2USP2 | |
| SCHEMBL2373613 | 0.73 | HPGD (0.41) | HPGDEPHX1CTSKSMN1; SMN2USP2 | |
| SCHEMBL689203 | 0.71 | USP2 (0.33) | SMN1; SMN2USP2 | |
| SCHEMBL4434089 | 0.71 | HPGD (0.39) | HPGDEPHX1CTSKSMN1; SMN2USP2 | |
| SCHEMBL689237 | 0.70 | — | — | |
| SCHEMBL8779874 | 0.68 | USP2 (0.40) | HPGDEPHX1CTSKSMN1; SMN2USP2 | |
| SCHEMBL16925538 | 0.67 | HPGD (0.50) | HPGDEPHX1SMN1; SMN2USP2 | |
| SCHEMBL4961794 | 0.66 | SMN1; SMN2 (0.38) | HPGDSMN1; SMN2MITFGAA | |
| SCHEMBL9056185 | 0.66 | KMT2A (0.44) | SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323980-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |