SCHEMBL18493454

SCHEMBL18493454

CCCCCCCCN(CCCCCCCC)c1ccc2cc(/C=C/c3cc[n+](CCCS(=O)(=O)O)cc3)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 4/20 0.49
KDM2A Q9Y2K7 4/20 0.49
CHRM2 P08172 2/20 0.47
CHRM4 P08173 2/20 0.47
CHRM5 P08912 2/20 0.47
CHRM1 P11229 2/20 0.47
CHRM3 P20309 2/20 0.47
APP P05067 3/20 0.47
INSR P06213 1/20 0.39
CHAT P28329 1/20 0.38
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
THRB P10828 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18493455 1.00 KDM4A (0.49) KDM4AKDM2ACHRM2CHRM4CHRM5
SCHEMBL83585 0.96 CHRM2 (0.52) KDM4AKDM2ACHRM2CHRM4CHRM5
SCHEMBL4298270 0.96 CHRM2 (0.52) KDM4AKDM2ACHRM2CHRM4CHRM5
Water SCHEMBL22655270 0.95 CHRM2 (0.51) KDM4AKDM2ACHRM2CHRM4CHRM5
Water SCHEMBL22655271 0.95 CHRM2 (0.51) KDM4AKDM2ACHRM2CHRM4CHRM5
SCHEMBL25174360 0.91 CHRM2 (0.57) KDM4AKDM2ACHRM2CHRM4CHRM5
SCHEMBL9016124 0.91 CHRM2 (0.57) KDM4AKDM2ACHRM2CHRM4CHRM5
SCHEMBL6418098 0.91 CHRM2 (0.57) KDM4AKDM2ACHRM2CHRM4CHRM5
SCHEMBL9016121 0.91 CHRM2 (0.57) KDM4AKDM2ACHRM2CHRM4CHRM5
SCHEMBL6418092 0.91 CHRM2 (0.57) KDM4AKDM2ACHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014561-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS UNIV WASHINGTON (US) 2026-01-15 US disclosed
US-12447469-B2 Methods and apparatus for single biological nanoparticle analysis UNIVERSITY OF WASHINGTON (US) 2025-10-21 US disclosed
US-20240374214-A1 IMPLANTABLE AND CONTINUOUS MULTI-ANALYTE MONITOR (MAM) SENSOR UNIV CALIFORNIA (US) 2024-11-14 US disclosed
US-20230251194-A1 OPTICAL ANALYSES OF PARTICLES AND VESICLES SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH 2023-08-10 US disclosed
WO-2023039393-A1 IMPLANTABLE AND CONTINUOUS MULTI-ANALYTE MONITOR (MAM) SENSOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-16 WO disclosed
US-11486829-B2 Optical analyses of particles and vesicles SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (US) 2022-11-01 US disclosed
EP-3775838-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS University of Washington (US) 2021-02-17 EP disclosed
US-20210016276-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS UNIVERSITY OF WASHINGTON (US) 2021-01-21 US disclosed
US-20200173923-A1 OPTICAL ANALYSES OF PARTICLES AND VESICLES SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH 2020-06-04 US disclosed
WO-2019199499-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS UNIVERSITY OF WASHINGTON (US) 2019-10-17 WO disclosed
US-10429302-B2 Optical analyses of particles and vesicles SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (US) 2019-10-01 US disclosed
EP-3335028-A1 OPTICAL ANALYSES OF PARTICLES AND VESICLES Scintillon Institute for Biomedical and Bioenergy Research (US) 2018-06-20 EP disclosed
WO-2017027622-A1 OPTICAL ANALYSES OF PARTICLES AND VESICLES SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (US) 2017-02-16 WO disclosed
US-20170045451-A1 OPTICAL ANALYSES OF PARTICLES AND VESICLES SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH 2017-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014561-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS CD63, SELL, LAMP2 KDM4A 4694/4885KDM2A 4203/4885CHRM2 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.