Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 3/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83585 | 1.00 | CHRM2 (0.52) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Water SCHEMBL22655270 | 0.99 | CHRM2 (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Water SCHEMBL22655271 | 0.99 | CHRM2 (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18493455 | 0.96 | KDM4A (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18493454 | 0.96 | KDM4A (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL26644133 | 0.90 | CHRM2 (0.62) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29860214 | 0.90 | CHRM2 (0.52) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18796804 | 0.90 | CHRM2 (0.52) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18796805 | 0.90 | CHRM2 (0.52) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Water SCHEMBL7040807 | 0.89 | CHRM2 (0.61) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227469-A1 | CELLS AND ASSAYS FOR USE IN DETECTING LONG QT SYNDROME | THE J. DAVID GLADSTONE INSTITUTES | 2009-09-10 | — | — | US | disclosed |
| WO-2006037226-A1 | USE OF QUANTUM DOTS FOR BIOLOGICAL LABELS AND SENSORS | MCGILL UNIVERSITY (CA) | 2006-04-13 | — | — | WO | disclosed |