Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25314147 | 0.86 | GLA (0.53) | GLAALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL17347284 | 0.82 | GLA (0.56) | GLAALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL28651135 | 0.76 | ALDH1A1 (0.61) | GLAALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL3293088 | 0.73 | ALDH1A1 (0.63) | GLAALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL2070952 | 0.72 | ALDH1A1 (0.61) | GLAALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL28282461 | 0.72 | ALDH1A1 (1.00) | GLAALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL10651010 | 0.72 | ALDH1A1 (0.61) | GLAALDH1A1KDM4EGRIN2DGRIN3B | |
| SCHEMBL11645181 | 0.72 | ALDH1A1 (0.61) | GLAALDH1A1KDM4EGRIA1GRIA2 | |
| SCHEMBL909616 | 0.71 | ALDH1A1 (0.56) | GLAALDH1A1KDM4EGRIA1GRIA2 | |
| SCHEMBL9949061 | 0.69 | ERCC1 (0.50) | GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324010-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010009968-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| WO-2009138219-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-19 | — | — | WO | disclosed |