Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18497827 | 0.85 | IRAK4 (0.45) | IDO1 | |
| SCHEMBL17729205 | 0.84 | IDO1 (0.69) | IDO1CHRM4 | |
| SCHEMBL18497849 | 0.82 | IRAK4 (0.45) | IDO1 | |
| SCHEMBL18497792 | 0.81 | IDO1 (0.61) | IDO1 | |
| SCHEMBL18497791 | 0.81 | IDO1 (0.61) | IDO1 | |
| SCHEMBL32674622 | 0.80 | IDO1 (0.48) | IDO1 | |
| SCHEMBL23699132 | 0.78 | IDO1 (0.57) | IDO1 | |
| SCHEMBL29862743 | 0.76 | IDO1 (0.60) | IDO1 | |
| SCHEMBL23360518 | 0.76 | IDO1 (0.60) | IDO1 | |
| SCHEMBL23699112 | 0.76 | IDO1 (0.57) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | disclosed |