Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15714705 | 0.79 | MCL1 (0.54) | MCL1MAPTALDH1A1LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL11680072 | 0.73 | ALDH1A1 (0.51) | MCL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21052519 | 0.71 | MCL1 (0.57) | MCL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1965264 | 0.70 | MCL1 (0.56) | MCL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14321375 | 0.69 | MCL1 (0.55) | MCL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10003520 | 0.68 | MCL1 (0.54) | MCL1ALDH1A1KMT2AMAPK1TSHR | |
| SCHEMBL14321006 | 0.68 | MCL1 (0.54) | MCL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6072487 | 0.68 | MCL1 (0.54) | MCL1MAPTALDH1A1LMNAGABRA1 | |
| SCHEMBL14321653 | 0.68 | MCL1 (0.54) | MCL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6617724 | 0.67 | MCL1 (0.53) | MCL1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567301-B2 | Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-14 | — | — | US | disclosed |