Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722117 | 0.93 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL18501157 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL18501155 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15966639 | 0.85 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15966638 | 0.85 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15722107 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15722121 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15722122 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15703388 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL7695305 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567336-B2 | Conjugated TLR7 and/or TLR8 and TLR2 agonists | INVIVOGEN (FR) | 2017-02-14 | — | — | US | disclosed |