⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16577377 | 0.91 | SCN10A (0.30) | — | |
| SCHEMBL16577541 | 0.90 | SCN10A (0.34) | — | |
| SCHEMBL16577491 | 0.84 | — | — | |
| SCHEMBL16577483 | 0.84 | — | — | |
| SCHEMBL18501422 | 0.84 | SCN10A (0.35) | — | |
| SCHEMBL15586047 | 0.83 | PRCP (0.35) | — | |
| SCHEMBL18501423 | 0.83 | LPL (0.39) | — | |
| SCHEMBL18501417 | 0.83 | LPL (0.39) | — | |
| SCHEMBL18501424 | 0.81 | SCN10A (0.34) | — | |
| SCHEMBL18501409 | 0.81 | SCN10A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738629-B2 | Bridged ring compounds as Hepatitis C virus inhibitors, pharmaceutical compositions and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-08-22 | — | — | US | disclosed |
| US-20170044140-A1 | BRIDGED RING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-02-16 | — | — | US | disclosed |