Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19939276 | 0.88 | HRH3 (0.36) | — | |
| SCHEMBL12885052 | 0.85 | HRH3 (0.37) | DRD2DRD3DRD4 | |
| SCHEMBL16996991 | 0.83 | TSHR (0.38) | — | |
| SCHEMBL19115749 | 0.83 | — | — | |
| SCHEMBL23847149 | 0.82 | — | — | |
| SCHEMBL12885055 | 0.80 | HRH3 (0.39) | DRD2DRD3DRD4 | |
| SCHEMBL24359072 | 0.79 | PIK3CD (0.38) | — | |
| SCHEMBL24995546 | 0.79 | ESRRG (0.31) | — | |
| SCHEMBL24854965 | 0.77 | JAK2 (0.35) | — | |
| SCHEMBL22388202 | 0.77 | PIK3CD (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567334-B2 | Quinolone derivatives as fibroblast growth factor receptor inhibitors | PRINCIPIA BIOPHARMA, INC. (US) | 2017-02-14 | — | — | US | disclosed |