Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854943 | 0.89 | PIK3CD (0.32) | PIK3CDPOLBALDH1A1 | |
| SCHEMBL23588630 | 0.86 | POLB (0.40) | PIK3CDPOLBALDH1A1 | |
| SCHEMBL20075879 | 0.86 | POLB (0.40) | PIK3CDPOLBALDH1A1 | |
| SCHEMBL20906896 | 0.86 | POLB (0.40) | PIK3CDPOLBALDH1A1 | |
| SCHEMBL21038822 | 0.82 | POLB (0.44) | PIK3CDPOLBALDH1A1 | |
| SCHEMBL25900547 | 0.80 | PIK3CD (0.34) | PIK3CDPOLBALDH1A1 | |
| SCHEMBL23588937 | 0.79 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL16996991 | 0.79 | TSHR (0.38) | PIK3CD | |
| SCHEMBL13803188 | 0.79 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL18501657 | 0.79 | DRD2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002382-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUNDS | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-01-05 | — | — | US | disclosed |
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002382-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUNDS | KRAS, NRAS, HRAS | PIK3CD 543/4885POLB 4149/4885ALDH1A1 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.