Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.79 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.79 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | BLM | P54132 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.71 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.70 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23845910 | 1.00 | GPBAR1 (0.79) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL18502187 | 1.00 | GPBAR1 (0.79) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL17789408 | 1.00 | GPBAR1 (0.79) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL19577212 | 0.97 | GPBAR1 (0.78) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL29350826 | 0.95 | GPBAR1 (0.75) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL1653681 | 0.94 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL23312339 | 0.94 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL8207308 | 0.94 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL23312348 | 0.94 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL20375456 | 0.94 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170042923-A1 | REDUCED TOXICITY MOLECULAR CONJUGATES OF ANTI-FUNGAL AGENTS | LEHIGH UNIVERSITY | 2017-02-16 | — | — | US | disclosed |
| US-20170042923-A1 | REDUCED TOXICITY MOLECULAR CONJUGATES OF ANTI-FUNGAL AGENTS | LEHIGH UNIVERSITY | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170042923-A1 | REDUCED TOXICITY MOLECULAR CONJUGATES OF ANTI-FUNGAL AGENTS | ANTXR2, FABP7, ERG28 | GPBAR1 3508/4885SLC10A2 3783/4885SLC10A1 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.