Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960760 | 0.83 | GPR52 (0.53) | F10MAP4K4ATRMEN1KMT2A | |
| SCHEMBL12918989 | 0.81 | ABCB1 (0.49) | F10MAP4K4SMN1; SMN2ATRPTK2 | |
| SCHEMBL961496 | 0.81 | SMYD2 (0.56) | MAP4K4DRD4GPR52DRD2HTR3A | |
| SCHEMBL963739 | 0.80 | F10 (0.62) | F10MAP4K4ATRMEN1KMT2A | |
| SCHEMBL12919090 | 0.77 | MAP4K4 (0.54) | MAP4K4KMT2AGPR52 | |
| SCHEMBL12918986 | 0.75 | DRD4 (0.51) | F10MAP4K4ATRPTK2DRD4 | |
| SCHEMBL963885 | 0.75 | F10 (0.51) | F10MAP4K4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12919097 | 0.74 | GPR52 (0.51) | F10DRD4GPR52DRD2POLB | |
| SCHEMBL958719 | 0.73 | MAP4K4 (0.54) | MAP4K4ATRDRD4MEN1KMT2A | |
| SCHEMBL959854 | 0.73 | F10 (0.51) | F10MAP4K4ATRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |