SCHEMBL18503104

SCHEMBL18503104

CCOC(=O)c1cccc(Cl)c1COc1ccn(O)n1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
PDE4B Q07343 1/20 0.39
BAZ2B Q9UIF8 1/20 0.38
BAZ2A Q9UIF9 1/20 0.38
GABRA5 P31644 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
ALOX12 P18054 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
NR1H4 Q96RI1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504967 0.91 ALDH1A1 (0.44) ALDH1A1L3MBTL1KMT2AATMTSHR
SCHEMBL18504649 0.88 TDP1 (0.41) ALDH1A1KMT2ATDP1HTTHPGD
SCHEMBL18504238 0.88 TSHR (0.43) ALDH1A1TSHRGABRA5HSD17B10MAPT
SCHEMBL22564472 0.88 ALDH1A1 (0.43) ALDH1A1L3MBTL1KMT2AATMTSHR
SCHEMBL18504415 0.87 TSHR (0.42) ALDH1A1TSHRGABRA5MRGPRX4HSD17B10
SCHEMBL18504960 0.86 TSHR (0.41) ALDH1A1L3MBTL1KMT2AATMTSHR
SCHEMBL18504663 0.86 ALDH1A1 (0.44) ALDH1A1L3MBTL1KMT2AATMTSHR
SCHEMBL18504659 0.86 TSHR (0.41) ALDH1A1KMT2ATSHRGABRA5HSD17B10
SCHEMBL18504253 0.86 TSHR (0.41) ALDH1A1L3MBTL1KMT2ATSHRGABRA5
SCHEMBL18504669 0.86 TSHR (0.39) ALDH1A1L3MBTL1KMT2AATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed