SCHEMBL18503379

SCHEMBL18503379

Cc1ccc(CCC2CCC(C3CCC(C)CC3)CC2)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 10/20 0.42
HTR2C P28335 10/20 0.42
MAOB P27338 2/20 0.35
MAOA P21397 1/20 0.34
OPRM1 P35372 1/20 0.31
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
TAS1R2 Q8TE23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21019437 0.96 HTR2A (0.42) HTR2AHTR2CMAOBMAOAOPRM1
SCHEMBL21430438 0.86 MAOB (0.39) HTR2AHTR2CMAOB
SCHEMBL18503383 0.84 HTR2A (0.39) HTR2AHTR2CMAOBMAOA
SCHEMBL10019544 0.84 HTR2A (0.42) HTR2AHTR2CMAOBMAOAOPRM1
SCHEMBL8153366 0.82 HTR2A (0.56) HTR2AHTR2C
SCHEMBL19195164 0.82 HTR2A (0.36) HTR2AHTR2CMAOBMAOA
SCHEMBL10091175 0.81 MAOA (0.51) HTR2AHTR2CMAOBMAOA
SCHEMBL8146281 0.79 HTR2A (0.43) HTR2AHTR2C
SCHEMBL13111393 0.78 HTR2A (0.33) HTR2AHTR2C
SCHEMBL18374089 0.77 MAOB (0.40) HTR2AHTR2CMAOBMAOAFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-11702597-B2 Azo dye MERCK PATENT GMBH (DE) 2023-07-18 US disclosed
US-11702597-B2 Azo dye MERCK PATENT GMBH (DE) 2023-07-18 US disclosed
US-11667845-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
US-11667845-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
US-20230053362-A1 DICHROIC DYE COMPOSITION MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-20230056437-A1 AZO DYE MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-11168257-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2021-11-09 US disclosed
US-20210238481-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (JP) 2021-08-05 US disclosed
US-10982150-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
EP-3487955-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-05-20 EP disclosed
WO-2020064591-A1 AZO DYE MERCK PATENT GMBH (DE) 2020-04-02 WO disclosed
EP-3475389-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-02-26 EP disclosed
WO-2019243216-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-12-26 WO disclosed
WO-2019238567-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-12-19 WO disclosed
US-20190241811-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-08-08 US disclosed
US-20190153320-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-05-23 US disclosed
WO-2018015320-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-01-25 WO disclosed
US-20170045765-A1 LCD DEVICE DIC CORPORATION (JP) 2017-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238481-A1 LIQUID CRYSTALLINE MEDIUM NEFM, CCNI, MYT1 HTR2A 558/4885HTR2C 306/4885MAOB 327/4885
US-11667845-B2 Liquid crystalline medium NEFM, CCNI, MYT1 HTR2A 558/4885HTR2C 306/4885MAOB 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.