Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91857 | 0.92 | MAOB (0.39) | BACE1MAOBCHKAGRM2HTR2A | |
| SCHEMBL8452464 | 0.87 | PTGES2 (0.42) | BACE1MAOBCHKAGRM2HTR2A | |
| SCHEMBL8452473 | 0.87 | PTGES2 (0.42) | BACE1MAOBCHKAGRM2HTR2A | |
| SCHEMBL14597272 | 0.85 | SLC6A2 (0.34) | BACE1MAOBCHKAGRM2HTR2A | |
| SCHEMBL10645691 | 0.85 | HRH3 (0.46) | MAOBPDE3BPDE3AKDM1A | |
| SCHEMBL10645700 | 0.85 | HRH3 (0.46) | MAOBPDE3BPDE3AKDM1A | |
| SCHEMBL7912858 | 0.83 | BACE1 (0.37) | BACE1MAOBCHKAGRM2HTR2A | |
| SCHEMBL7912861 | 0.83 | BACE1 (0.37) | BACE1MAOBCHKAGRM2HTR2A | |
| SCHEMBL7912854 | 0.83 | BACE1 (0.37) | BACE1MAOBCHKAGRM2HTR2A | |
| SCHEMBL7912851 | 0.83 | BACE1 (0.37) | BACE1MAOBCHKAGRM2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170045765-A1 | LCD DEVICE | DIC CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |