Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503380 | 0.92 | BACE1 (0.39) | MAOBGPR84GRM2HTR2ARARB | |
| SCHEMBL19820867 | 0.83 | FASN (0.41) | GRM2HTR2ARARBHRH3S1PR1 | |
| SCHEMBL21430438 | 0.83 | MAOB (0.39) | MAOBGPR84HTR2ASLC6A2SLC6A4 | |
| SCHEMBL10649307 | 0.83 | KDM1A (0.42) | MAOBGPR84HRH3KDM1A | |
| SCHEMBL10649312 | 0.83 | KDM1A (0.42) | MAOBGPR84HRH3KDM1A | |
| SCHEMBL15581287 | 0.82 | RARB (0.38) | MAOBGPR84RARBS1PR1FFAR4 | |
| SCHEMBL19820868 | 0.82 | FASN (0.44) | GRM2HTR2ARARBHRH3S1PR1 | |
| SCHEMBL8452464 | 0.82 | PTGES2 (0.42) | MAOBGPR84GRM2HTR2ARARB | |
| SCHEMBL8452473 | 0.82 | PTGES2 (0.42) | MAOBGPR84GRM2HTR2ARARB | |
| SCHEMBL19820861 | 0.82 | FASN (0.40) | GRM2HTR2ARARBHRH3FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10988692-B2 | Liquid crystal medium and liquid crystal device | MERCK PATENT GMBH (DE) | 2021-04-27 | — | — | US | disclosed |
| EP-3383970-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2021-03-31 | — | — | EP | disclosed |
| US-20200248077-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-08-06 | — | — | US | disclosed |
| US-10711196-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2020-07-14 | — | — | US | disclosed |
| EP-3455328-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2020-03-04 | — | — | EP | disclosed |
| US-10450508-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
| WO-2019179962-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | WO | disclosed |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| US-10343982-B2 | Compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
| EP-3071668-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-07-18 | — | — | EP | disclosed |
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
| US-7270856-B2 | Cyclobutane derivatives | MERCK PATENT GMBH (DE) | 2007-09-18 | — | — | US | disclosed |
| US-7250198-B2 | For electrooptical display | MERCK PATENT GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-7189440-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7182885-B2 | Fluorinated indenes and 1,7-dihydroindacenes of negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2007-02-27 | — | — | US | disclosed |
| US-7179511-B2 | For use in electro-optical displays | MERCK PATENT GMBH (DE) | 2007-02-20 | — | — | US | disclosed |
| US-20070034829-A1 | liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070034828-A1 | Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
| US-7166337-B2 | Liquid-crystal composition, methods of adjusting the resistance, and substituted phenols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-01-23 | — | — | US | disclosed |
| US-20070001149-A1 | Liquid-crystal medium containing monofluoroterphenyl compounds | MERCK PATENT GMBH (DE) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450508-B2 | Bimesogenic compounds and mesogenic media | SP1, FOXM1, S100A11 | MAOB 3238/4885GPR84 3859/4885GRM2 140/4885 |
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | ZYX, F3, YBX1 | MAOB 647/4885GPR84 3397/4885GRM2 1935/4885 |
| US-10343982-B2 | Compounds and mesogenic media | MTX1, NEFM, MTX2 | MAOB 535/4885GPR84 2347/4885GRM2 1116/4885 |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | SP1, FOXM1, S100A11 | MAOB 3274/4885GPR84 3723/4885GRM2 131/4885 |
| US-10711196-B2 | Bimesogenic compounds and mesogenic media | BMP2, NEFM, MTX1 | MAOB 578/4885GPR84 2529/4885GRM2 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.