Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985633 | 0.81 | HPGD (0.42) | NPC1RAB9AKDM1AHSD11B1GRM1 | |
| SCHEMBL18503388 | 0.80 | MEN1 (0.47) | NPC1RAB9AKDM1AHSD11B1MEN1 | |
| SCHEMBL18503384 | 0.80 | NPC1 (0.49) | NPC1RAB9AKDM1AHSD11B1MEN1 | |
| SCHEMBL18503387 | 0.78 | TAS1R3 (0.39) | NPC1RAB9AKDM1AHSD11B1MEN1 | |
| SCHEMBL18503386 | 0.77 | MEN1 (0.47) | NPC1RAB9AKDM1AHSD11B1MEN1 | |
| SCHEMBL12205092 | 0.77 | HPGD (0.46) | NPC1RAB9AHSD11B1MEN1KMT2A | |
| SCHEMBL18084742 | 0.76 | KMT2A (0.58) | NPC1RAB9AHSD11B1MEN1KMT2A | |
| SCHEMBL802765 | 0.76 | ESR2 (0.46) | NPC1RAB9ACYP2D6 | |
| SCHEMBL15445840 | 0.74 | ESR2 (0.45) | KDM1ACYP2D6 | |
| SCHEMBL12999857 | 0.74 | ALOX5AP (0.35) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170045765-A1 | LCD DEVICE | DIC CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |