Riboprine

Riboprine

SCHEMBL18503566

CC(C)=CCNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.79
LMNA P02545 1/20 0.79
ALOX15 P16050 1/20 0.79
TSHR P16473 1/20 0.79
HTT P42858 1/20 0.79
RXFP1 Q9HBX9 1/20 0.79
SLC29A1 Q99808 3/20 0.70
ADORA3 P0DMS8 2/20 0.67
TDP1 Q9NUW8 1/20 0.67
ADORA2A P29274 1/20 0.66
ADORA2B P29275 1/20 0.66
ADORA1 P30542 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Riboprine SCHEMBL1763190 1.00 TP53 (0.79) TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL16805426 1.00 TP53 (0.79) TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL29552839 1.00 TP53 (0.79) TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL4815729 1.00 TP53 (0.79) TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL4599 1.00 TP53 (0.79) TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL18870819 1.00 TP53 (0.79) TP53LMNAALOX15TSHRHTT
Riboprine SCHEMBL4600 1.00 TP53 (0.79) TP53LMNAALOX15TSHRHTT
SCHEMBL25170535 0.99 TP53 (0.78) TP53LMNAALOX15TSHRHTT
SCHEMBL31307032 0.99 TP53 (0.78) TP53LMNAALOX15TSHRHTT
SCHEMBL8706995 0.99 TP53 (0.78) TP53LMNAALOX15TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US disclosed
US-20170044619-A1 PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2017-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 TP53 411/4885LMNA 571/4885ALOX15 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.