Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CDA | P32320 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499007 | 1.00 | LMNA (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL20454433 | 1.00 | LMNA (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL19407899 | 1.00 | LMNA (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL3499005 | 1.00 | LMNA (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL19399427 | 0.92 | P2RY6 (0.46) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL16940282 | 0.92 | P2RY6 (0.46) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL15023808 | 0.91 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL19617039 | 0.91 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL31729061 | 0.91 | P2RY6 (0.45) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL30274887 | 0.91 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044619-A1 | PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-02-16 | — | — | US | disclosed |