Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.49 |
| ▸ | TK2 | O00142 | 2/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965358 | 1.00 | PYGM (0.55) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18512964 | 1.00 | PYGM (0.55) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL26369667 | 1.00 | PYGM (0.55) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL1965361 | 1.00 | PYGM (0.55) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18512965 | 1.00 | PYGM (0.55) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL23883104 | 0.91 | PYGM (0.53) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL11883660 | 0.90 | PYGM (0.57) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL26370134 | 0.90 | CDA (0.46) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL30130603 | 0.89 | PYGM (0.56) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL11877280 | 0.89 | PYGM (0.56) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044619-A1 | PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-02-16 | — | — | US | disclosed |