Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504976 | 0.91 | MAPT (0.36) | NPC1NR1H4KDM4EPOLBMAPT | |
| SCHEMBL18504645 | 0.90 | KDM4E (0.39) | NR1H4KDM4EPOLBNPSR1ALDH1A1 | |
| SCHEMBL18504647 | 0.88 | TSHR (0.40) | KDM4EL3MBTL1GABRA5ALDH1A1TSHR | |
| SCHEMBL22564030 | 0.88 | NPC1 (0.35) | NPC1NR1H4KDM4EPOLBMAPT | |
| SCHEMBL18504678 | 0.88 | GABRA5 (0.37) | NPC1NR1H4KDM4EPOLBMAPT | |
| SCHEMBL18500393 | 0.87 | NR1H4 (0.41) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL18500756 | 0.87 | KDM4E (0.35) | NPC1KDM4EPOLBMAPTNPSR1 | |
| SCHEMBL18504464 | 0.87 | NR1H4 (0.35) | NR1H4LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL18504390 | 0.87 | NPC1 (0.36) | NPC1NR1H4KDM4EPOLBMAPT | |
| SCHEMBL18504968 | 0.87 | MAPT (0.38) | NPC1KDM4EPOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |