Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504554 | 0.89 | LMNA (0.40) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL18504621 | 0.89 | HTT (0.40) | KDM4EL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18504392 | 0.88 | KMT2A (0.35) | KDM4ESMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL18504734 | 0.88 | KDM4E (0.38) | KDM4EL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL18504683 | 0.88 | KDM4E (0.38) | KDM4EL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22564396 | 0.87 | KDM4E (0.37) | KDM4EL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18504253 | 0.87 | TSHR (0.41) | KDM4EL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18504192 | 0.87 | HCRTR1 (0.38) | KDM4EL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL18504775 | 0.86 | IRAK4 (0.48) | SMN1; SMN2KMT2AMEN1MKNK1MKNK2 | |
| SCHEMBL18505268 | 0.86 | HCRTR1 (0.40) | KDM4EL3MBTL1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |