Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504746 | 0.90 | NR1H4 (0.31) | NR1H4 | |
| SCHEMBL22564206 | 0.88 | LIG1 (0.33) | LIG1PDE5AMMP3HDAC8 | |
| SCHEMBL18504956 | 0.87 | KDM4E (0.36) | KDM4ESMN1; SMN2 | |
| SCHEMBL18504644 | 0.87 | NR1H4 (0.36) | NR1H4KDM4E | |
| SCHEMBL18504725 | 0.86 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL18504745 | 0.86 | PARP1 (0.32) | HDAC8NR1H4HDAC11KDM4ESMN1; SMN2 | |
| SCHEMBL18504739 | 0.86 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL18504821 | 0.86 | HDAC3 (0.41) | LIG1PDE5AMMP3HDAC8KDM4E | |
| SCHEMBL18504857 | 0.85 | PDE5A (0.34) | LIG1PDE5AMMP3HDAC8NR1H4 | |
| SCHEMBL18504583 | 0.85 | ALDH1A1 (0.33) | LIG1PDE5AMMP3HDAC8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |