SCHEMBL18504737

SCHEMBL18504737

CCSc1cccc(C(=O)Br)c1COc1ccn(O)n1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.36
MAPK1 P28482 3/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
MITF O75030 1/20 0.36
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HPGD P15428 6/20 0.35
ALDH1A1 P00352 4/20 0.35
ALOX15 P16050 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NR1H4 Q96RI1 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504170 0.90 HSD17B10 (0.37) HSD17B10MAPK1LMNAHTTMITF
SCHEMBL18504515 0.89 HSD17B10 (0.36) HSD17B10MAPK1LMNAHTTMITF
SCHEMBL18504712 0.89 HSD17B10 (0.36) HSD17B10MAPK1LMNAHTTMITF
SCHEMBL18505000 0.89
SCHEMBL18504521 0.89 L3MBTL1 (0.32) HSD17B10LMNAHTTTSHRNPSR1
SCHEMBL18500715 0.88 HSD17B10 (0.41) HSD17B10MAPK1LMNAHTTMITF
SCHEMBL22564517 0.88 HSD17B10 (0.33) HSD17B10MAPK1LMNAHTTMITF
SCHEMBL18504819 0.87 HPGD (0.38) HSD17B10MAPK1LMNAHTTMITF
SCHEMBL18504389 0.87 TSHR (0.39) HSD17B10MAPK1LMNAHTTMITF
SCHEMBL18504680 0.86 HPGD (0.38) HSD17B10MAPK1LMNAHTTMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed