⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984129 | 0.74 | — | — | |
| SCHEMBL11093808 | 0.72 | ALDH1A1 (0.58) | — | |
| SCHEMBL4722200 | 0.70 | — | — | |
| SCHEMBL1007930 | 0.69 | — | — | |
| SCHEMBL5870795 | 0.69 | — | — | |
| SCHEMBL2396413 | 0.66 | ALDH1A1 (0.43) | — | |
| SCHEMBL11497234 | 0.66 | — | — | |
| SCHEMBL11667263 | 0.64 | — | — | |
| SCHEMBL289428 | 0.63 | — | — | |
| SCHEMBL156583 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | claimed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | claimed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| CN-103641795-A | Acetophenone derivatives containing 1,2,3-thiadiazole and preparation method and use thereof | UNIV NANKAI | 2014-03-19 | — | — | CN | claimed |
| EP-0047560-B1 | PROCESS FOR THE PREPARATION OF 7-ACYLAMINO-3-(THIO-SUBSTITUTED)METHYL-3-CEPHEM-4-CARBOXYLIC ACID 1-OXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1985-04-10 | — | — | EP | claimed |
| US-4379923-A | Preparation of 7-acylamino-3-(thio-substituted)-methyl 3-cephem-4-carboxylic acid-1-oxide derivatives | GIST-BROCADES N.V. (NL) | 1983-04-12 | — | — | US | claimed |
| EP-0047560-A2 | Process for the preparation of 7-acylamino-3-(thio-substituted)methyl-3-cephem-4-carboxylic acid 1-oxide derivatives | GIST-BROCADES N.V. (NL) | 1982-03-17 | — | — | EP | claimed |
| US-11365175-B2 | Aromatic amides having a fungicidal activity, their agronomic compositions and relative preparation method | ISAGRO S.P.A. (IT) | 2022-06-21 | — | — | US | disclosed |
| US-20200354314-A1 | AROMATIC AMIDES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE PREPARATION METHOD | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2020-11-12 | — | — | US | disclosed |
| EP-3704099-A1 | AROMATIC AMIDES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE PREPARATION METHOD | ISAGRO S.p.A. (IT) | 2020-09-09 | — | — | EP | disclosed |
| EP-3080119-B1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-07-08 | — | — | EP | disclosed |
| CN-111356683-A | Aromatic amides with fungicidal activity, their agricultural compositions and related preparation methods | 伊萨格罗股份公司 | 2020-06-30 | — | — | CN | disclosed |
| EP-3080128-B1 | IMIDAZOPYRIDAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-24 | — | — | EP | disclosed |
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC. | 2008-07-24 | — | — | US | disclosed |
| EP-1874780-A1 | 4-PIPERAZINYLTHIENO[2,3-D]PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2008001076-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2008-01-03 | — | — | WO | disclosed |
| WO-2006100591-A1 | 4-PIPERAZINNYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| EP-0047560-B1 | PROCESS FOR THE PREPARATION OF 7-ACYLAMINO-3-(THIO-SUBSTITUTED)METHYL-3-CEPHEM-4-CARBOXYLIC ACID 1-OXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1985-04-10 | — | — | EP | disclosed |
| US-4379923-A | Preparation of 7-acylamino-3-(thio-substituted)-methyl 3-cephem-4-carboxylic acid-1-oxide derivatives | GIST-BROCADES N.V. (NL) | 1983-04-12 | — | — | US | disclosed |
| EP-0047560-A2 | Process for the preparation of 7-acylamino-3-(thio-substituted)methyl-3-cephem-4-carboxylic acid 1-oxide derivatives | GIST-BROCADES N.V. (NL) | 1982-03-17 | — | — | EP | disclosed |