Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506132 | 0.83 | PIK3C3 (0.37) | DYRK1AADORA3MAPK1PIK3CAMAPK8 | |
| SCHEMBL23934187 | 0.81 | DYRK1A (0.34) | DYRK1AADORA3POLBMAPK1PIK3CA | |
| SCHEMBL31141497 | 0.81 | DDR1 (0.33) | POLBDDR1RAB9A | |
| SCHEMBL18498693 | 0.81 | DDR1 (0.33) | POLBDDR1RAB9A | |
| SCHEMBL17309745 | 0.78 | SMN1; SMN2 (0.34) | POLBMAPK1NPC1RAB9AMAPK14 | |
| SCHEMBL29431639 | 0.78 | SMN1; SMN2 (0.34) | POLBMAPK1NPC1RAB9AMAPK14 | |
| SCHEMBL18819410 | 0.76 | TLR8 (0.33) | ELANEPOLBRAB9AMAPK14 | |
| SCHEMBL18506131 | 0.74 | AGPAT2 (0.44) | DYRK1AADORA3POLBDDR1CYP1A2 | |
| SCHEMBL9952930 | 0.73 | NPC1 (0.43) | POLBNPC1GAA | |
| SCHEMBL20144323 | 0.72 | POLB (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |