Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 5/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18498723 | 0.83 | RORC (0.43) | AGPAT2BRAFACACBDYRK1AADORA3 | |
| SCHEMBL18506069 | 0.82 | AGPAT2 (0.41) | AGPAT2ACACBDDR1CYP1A2CYP2C19 | |
| SCHEMBL18506070 | 0.81 | AGPAT2 (0.39) | AGPAT2DDR1CYP1A2CYP2C19 | |
| SCHEMBL18506152 | 0.80 | POLB (0.36) | BRAFADORA3POLBCYP1A2CYP2C9 | |
| SCHEMBL14677508 | 0.77 | HTR2B (0.39) | AGPAT2DDR1CYP1A2CYP2C19 | |
| SCHEMBL20042379 | 0.76 | ACVR1 (0.32) | AGPAT2BRAFPOLBRORCCYP2C9 | |
| SCHEMBL18506068 | 0.76 | PDE10A (0.39) | AGPAT2POLBDDR1CYP1A2CYP2C19 | |
| SCHEMBL18819856 | 0.76 | CNR2 (0.41) | AGPAT2DDR1CYP1A2CYP2C19 | |
| SCHEMBL14678088 | 0.76 | POLB (0.40) | AGPAT2POLBDDR1CYP1A2CYP2C19 | |
| SCHEMBL9280305 | 0.74 | AGPAT2 (0.38) | AGPAT2POLBDDR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |