Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14329534 | 0.82 | TSHR (0.59) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL27562488 | 0.81 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13067061 | 0.78 | TSHR (0.63) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL36668 | 0.78 | TSHR (0.63) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9058588 | 0.78 | TSHR (0.63) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23734812 | 0.78 | TSHR (0.63) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11983797 | 0.76 | TSHR (0.67) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13383371 | 0.76 | TSHR (0.80) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL19414927 | 0.76 | TSHR (0.67) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13400269 | 0.76 | TSHR (0.67) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027482-A1 | ANIONIC CURABLE COMPOSITIONS | DESIGNER MOLECULES, INC. (US) | 2017-02-16 | — | — | WO | disclosed |