Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732216 | 0.92 | DRD2 (0.57) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL30712216 | 0.92 | DRD2 (0.57) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL18507834 | 0.86 | DRD2 (0.52) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL1038841 | 0.86 | DRD2 (0.54) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL29433201 | 0.86 | DRD2 (0.54) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL14772949 | 0.85 | DRD2 (0.52) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL251608 | 0.85 | DRD2 (0.52) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL15854760 | 0.85 | DRD2 (0.52) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL18507945 | 0.85 | DRD2 (0.54) | DRD2DRD4DRD3ACHEMAOB | |
| SCHEMBL30176701 | 0.85 | DRD2 (0.52) | DRD2DRD4DRD3ACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025987-A1 | PROCESS FOR THE PREPARATION OF BREXPIPRAZOLE | MYLAN LABORATORIES LIMITED (IN) | 2017-02-16 | — | — | WO | disclosed |