Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.78 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.60 |
| ▸ | CDC25A | P30304 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | POLA1 | P09884 | 1/20 | 0.58 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26753756 | 0.92 | VDR (0.81) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL15043312 | 0.90 | VDR (0.76) | VDRUSP2ST6GAL1CDC25AALDH1A1 | |
| SCHEMBL7758755 | 0.90 | VDR (0.76) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL15976037 | 0.90 | VDR (0.79) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL12192042 | 0.89 | VDR (0.81) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL26753754 | 0.89 | VDR (0.81) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL18576366 | 0.89 | VDR (0.81) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL11453881 | 0.89 | VDR (0.80) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL11467719 | 0.89 | VDR (0.80) | VDRUSP2ST6GAL1CDC25AABCC4 | |
| SCHEMBL11472581 | 0.89 | VDR (0.80) | VDRUSP2ST6GAL1CDC25AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027396-A1 | METHODS FOR PREPARATION OF BILE ACIDS AND DERIVATIVES THEREOF | INTERCEPT PHARMACEUTICALS, INC. (US) | 2017-02-16 | — | — | WO | disclosed |