Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853988 | 0.97 | GPR52 (0.53) | GPR52SYKMAPTMEN1KMT2A | |
| SCHEMBL1849738 | 0.92 | GPR52 (0.55) | GPR52NR4A2MEN1KMT2AKDM4C | |
| SCHEMBL3210335 | 0.84 | GPR52 (0.58) | GPR52SCD | |
| SCHEMBL3209948 | 0.84 | GPR52 (0.48) | GPR52SYKMAPTMEN1KMT2A | |
| SCHEMBL1848119 | 0.83 | GPR52 (0.71) | GPR52MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1851359 | 0.81 | GPR52 (0.51) | GPR52SYKMAPTMEN1KMT2A | |
| SCHEMBL1848379 | 0.81 | GPR52 (0.69) | GPR52MAPTMEN1KMT2ASCD | |
| SCHEMBL1850413 | 0.80 | JMJD6 (0.46) | SYKMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL1851123 | 0.80 | GPR52 (0.75) | GPR52 | |
| SCHEMBL1855959 | 0.80 | JMJD6 (0.47) | SYKMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |